MTHFR Essentials Packages

Biome IQ’s products are focused on helping individuals with MTHFR mutations get the proper methylation and nutrients they need in order to detoxify their bodies and reduce their symptoms. We are the first company to create genetically specific protocols based on MTHFR gene mutations.

MTHFR C677C = normal MTHFR gene
MTHFR C677T = heterozygous mutation (one mutation)
MTHFR T677T = homozygous mutation (two mutations)
MTHFR A1298A = normal MTHFR gene
MTHFR A1298C = heterozygous mutation (one mutation)
MTHFR C1298C = homozygous mutation (two mutations)
MTHFR C677T + MTHFR A1298C = a compound heterozygous mutation

Individuals with two copies of 677C (677CC) have the most common genotype. 677TT individuals (homozygous) have lower MTHFR activity than CC or CT (heterozygous) individuals

MTHFR stands for methylenetetrahydrofolate reductase, which is an enzyme that plays a crucial role in processing amino acids, the building blocks of proteins. It is particularly important for a chemical reaction involving forms of the vitamin folate (vitamin B9). The MTHFR gene provides instructions for making this enzyme.

Causes:

● Genetic Mutations: Variations or mutations in the MTHFR gene can affect the enzyme's function. The most common mutations are C677T and A1298C. These mutations can lead to reduced activity of the MTHFR enzyme, affecting folate metabolism and homocysteine levels in the blood.

Symptoms:

● Elevated Homocysteine Levels: Individuals with MTHFR mutations may have elevated levels of homocysteine, an amino acid, which is associated with an increased risk of cardiovascular diseases.

● Potential Health Issues: Some studies suggest that MTHFR mutations may be linked to a variety of health issues, including cardiovascular diseases, certain pregnancy complications (like neural tube defects), and possibly mental health disorders. However, the evidence is not conclusive, and many people with MTHFR mutations do not experience any health problems.

Considerations:

● Folate Supplementation: People with MTHFR mutations may benefit from taking folate supplements, particularly in the form of methylfolate, which is more easily utilized by the body.

● Lifestyle and Diet: Maintaining a healthy lifestyle, including a balanced diet rich in folate (found in leafy greens, fruits, and fortified foods), can help manage potential risks associated with MTHFR mutations.

It's important to note that while MTHFR mutations can be associated with certain health conditions, they are not the sole cause, and many factors contribute to these conditions. Genetic testing and consultation with a healthcare provider can provide more personalized information and guidance.